Around 50% of people with ParkinsonÃ¢â‚¬â„¢s disease are also diagnosed with clinical depression. In many of them, the depression may occur months or years before ParkinsonÃ¢â‚¬â„¢s is diagnosed. While the anxiety and physical problems associated with having ParkinsonÃ¢â‚¬â„¢s disease are stressful and frustrating, most doctors agree that the depression that often accompanies ParkinsonÃ¢â‚¬â„¢s isnÃ¢â‚¬â„¢t a reaction to the diagnosis. Instead, they believe it is due to the changes in the brain that the disease causes. Proper treatment with antidepressants can alleviate the symptoms of depression.
A smaller percentage of those with ParkinsonÃ¢â‚¬â„¢s ultimately develop dementia. This can be one of the most difficult complications for the family to deal with. Dementia is marked by memory loss, impaired judgment and personality changes. It is associated with the later stages of ParkinsonÃ¢â‚¬â„¢s. Depression symptoms may also mimic dementia. If thatÃ¢â‚¬â„¢s the case, the symptoms may disappear with treatment of the depression.
To supplement standard treatment for ParkinsonÃ¢â‚¬â„¢s disease, many people have discovered that there are alternative and auxiliary treatments that can help manage their symptoms and give them a better quality of life for a longer period of time. While traditional practitioners who are schooled in Western methods tend to be skeptical of standard Eastern and other types of therapy, insurance companies are increasingly inclined to pay for alternative and complementary therapies Ã¢â‚¬â€œ which says a great deal about their possible effectiveness. Even most Western doctors agree that some of these treatments can help preserve function in many patients with ParkinsonÃ¢â‚¬â„¢s disease.
Eating a healthy diet is important for anyone, but those with ParkinsonÃ¢â‚¬â„¢s disease may have some particular concerns about diet. In particular, there is some evidence that high protein intake may interfere with the actions of L-dopa, the primary medication used to treat the symptoms of ParkinsonÃ¢â‚¬â„¢s.
These dopamine agonist drugs are not changed into dopamine inside the brain, unlike levodopa. They mimic the effects of dopamine inside the brain and allow the brain neurons to act as though sufficient amounts of dopamine were present. Dopamine agonists may be used in addition to levodopa therapy. In younger adults, dopamine agonists may be used instead of levodopa.
The various dopamine agonists vary in chemical structure, the range of side-effects that they cause, and their duration or length of action. For example, lisuride has a short duration, while pergolide has the longest duration.
The side-effects and benefits of a particular drug can vary from person to person. If one drug does not reduce symptoms or causes unwanted side-effects, then another dopamine agonist may be better suited.
The drug levodopa, also known as L-dopa, has been used since the 1960Ã¢â‚¬â„¢s as the primary drug treatment for Parkinson’s Disease.
Levodopa is a natural substance that is found in both plants and animals. The compound is actually a precursor to dopamine, and unlike dopamine, it is able to cross the blood-brain barrier. As a result, when given to people with Parkinson’s, levodopa is converted into dopamine by nerve cells in the brain.
When administered on its own, blood enzymes, known as AADCs, break down much of the levodopa prior it reaching the brain. As a result, only a small amount of levodopa crosses the blood-brain barrier and reaches the brain. However, combining levodopa with an decarboxylase enzyme inhibitor, such as carbidopa (Sinemet, or benserazide), allows more levodopa to reach the brain and helps reduce some of the side-effects of this therapy. Sinemet CR is a prolonged-release version of this drug.
Parkinson’s Disease results from the dopamine producing neurons in the substantia nigra becoming damaged or destroyed. An obvious treatment is to supplement the missing dopamine with medication.
Unfortunately, treatment with dopamine itself isn’t possible, because dopamine doesn’t cross the body’s blood-brain barrier. The tightly packed cells in the walls of the brain’s capillaries prevent certain substances from crossing into the brain, including dopamine. As a result, dopamine cannot be directly administered to a patient to boost their dopamine levels to reduce or reverse the effects of ParkinsonÃ¢â‚¬â„¢s.
However, a range of other medications and treatments can be used to treat ParkinsonÃ¢â‚¬â„¢s. Medications can also be used to manage problems cause by various ParkinsonÃ¢â‚¬â„¢s symptoms, including walking, general movement, and tremors by increasing the brain’s supply of dopamine.
Physical therapy and lifestyle changes should be looked on as the front-line defense against Parkinson’s. When physical therapy and lifestyle changes are not enough to combat or reduce the effects of Parkinson’s, your doctor will likely recommend certain medications, either alone or in combination. Eventually, as the disease progresses, a surgical procedure may be required.
A healthy diet and regular exercise are beneficial treatments for many health issues, and ParkinsonÃ¢â‚¬â„¢s is no exception to this rule. If you are suffering from ParkinsonÃ¢â‚¬â„¢s, ensure that you eat a healthy diet with lots of fruit and vegetables, and whole grains. These foods contain natural anti-oxidants that help protect against free radical damage. They are also high in fiber, which is important for helping prevent constipation.
If you take a fiber supplement, such as psyllium powder, Metamucil or Citrucel, be sure to introduce it gradually and drink plenty of fluids daily. Otherwise, your constipation actually may become worse. If you find that fiber helps your symptoms, use it on a regular basis for the best results.
There is no big hurry to begin treatment for the symptoms of Parkinson’s, since if treatment is not started immediately, then the person is not disadvantaged in any way. In fact, some experts recommend that a person waits until their symptoms are causing some difficulties with their daily living before they start treatment.
At this time no medication or drug has been shown to slow or stop the progression of this ParkinsonÃ¢â‚¬â„¢s. A variety of medications provide dramatic relief from the symptoms. Various physical therapies and muscle-strengthening exercises can also be beneficial in reducing the most troublesome symptoms of ParkinsonÃ¢â‚¬â„¢s. In some cases, surgery is an appropriate treatment.
There is no standard or Ã¢â‚¬Å“bestÃ¢â‚¬Â treatment for ParkinsonÃ¢â‚¬â„¢s, and various treatments are available in the following categories:
Risk Avoidance By reducing or eliminating as many of the risk factors as possible, it should be possible to greatly reduce your chances of developing Parkinson’s as a result of those causes. Physical Therapy
It is suspected that from sixty to ninety percent of individuals who develop ParkinsonÃ¢â‚¬â„¢s disease have problems at some point in time with their speech. For instance the affected person might speak in a monotone voice that is softer than normal- a condition known as hypophonia– they may hesitate before putting their thoughts into words, they may talk faster than normal or perhaps they might slur their words. Some people with ParkinsonÃ¢â‚¬â„¢s disease develop the tendency to repeat the same words over and over again while others develop a hoarseness quality to their speech.
Dysarthria is the name given to another speech impairment that makes itself known by such traits as a weak, slow and/or less than coherent speech pattern. Both the pitch and volume of speech can be affected by dysarthia.
Speech problems of this kind have a tendency to gradually get worse, and not better, with the passage of time. However with the guidance of a skilled speech therapist, individuals suffering with these problems can show improvements.